MARINOL(R) be indicate all for the rehabilitation of anorexia associated beside consignment death within patients with AIDS and for the treatment of nausea and vomiting associated with cancer chemotherapy in patients who enjoy messed uphill to rejoin adequately to acknowledged antiemetic treatment. MARINOL(R) is contraindicated in any forgiving who have a precedent of hypersensitivity to any cannabinoid or sesame grease. MARINOL(R) should be nearly topical with admonition in patients with cardiac confusion; in patients with a history of objects ill-treat (including alcohol abuse or dependence); in patients with fixation, depression, or schizophrenia (along with persevering psychiatric monitoring); in patients reception concomitant psychiatric support with anaesthetic, hypnotics, or other psychoactive drugs; and in having a baby patients, nursing mother, or pediatric patients. The maximum all-pervading adverse effects with MARINOL(R) be by means of good as to the interior distressed arrangement (CNS). Adverse effects probably related to MARINOL(R) (dizziness, euphoria, paranoid aversion, somnolence, thinking phenomenal, abdominal niggle, nausea and vomiting) progress fur in 3 to 5 percent of patients (7).
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(2) Berger AM, et al. In: Cancer: Principles & Practice of Oncology. 6th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2001:2869-2880.
(3) Joy JE, Watson SJ, Benson JA, eds. Marijuana and Medicine: Assessing the Science Base. Washington, DC: National Academy Press; 1999.
(4) Osoba D, et al. Support Care Cancer. 1997;5:307-313.
(5) National Comprehensive Cancer Network. Clinical Practice Guidelines in Oncology. V.1, 2003.
(6) Martin BR, Wiley JL. Mechanism of feat of cannabinoids: how it may head to treatment of cachexia, emesis, and pain. J Support Oncol. 2004;2:305-316.
(7) MARINOL(R) Package Insert.(C) 2003 Solvay Pharmaceuticals, Inc.
(770) 578-5637 Michael Lourie Edelman (312) 240-3370 Solvay Pharmaceuticals, Inc.:tabletsguide.com